1. Siegmann MJ, Zachs DP, Kenny JD, Lark ARS, Mir FA, Melonakos ED, Hozan M, Toledano S, Goldblum RR, Liu Y, Nolan MA, Cohen G, Choi J, White CG, Crowley EA, Carpenter AH, Toro BA, Syme CE, Brown EN, Nehs CJ. Neurophysiological Differences between Dexmedetomidine Sedation and Natural Sleep across the Rodent Lifespan: Implications for Aging and Perioperative Brain Health. Anesthesiol Perioper Sci (2026) 4(1):10. Epub 20260119. doi: 10.1007/s44254-025-00161-y. PMC12816052
  2. Lark ARS, Mir FA, Ambareen N, Tian F, Carpenter AH, Crowley EA, Toro BA, Syme CE, Aygar S, Thendral A, Smith K, White CG, Mahamdeh MS, Choi J, Nehs CJ. Ketogenic Interventions Enhance Rem Sleep in Females and Support Memory in Aged Rats. Front Aging Neurosci (2026) 18:1797686. Epub 20260410. doi: 10.3389/fnagi.2026.1797686. PMC13106476
  3. Kim MS, Kim K, Lee K, Nehs CJ, Pizzol D, Kang J, Yon DK. Trends in Physical Activity among South Korean Adults before, during, and after the Covid-19 Pandemic, 2009-2024: A Nationwide Representative Study. J Sci Med Sport (2026). Epub 20260108. doi: 10.1016/j.jsams.2026.01.001.
  4. Kim MS, Kim K, Byun S, Yim Y, Nehs CJ, Pizzol D, Kim T, Yon DK, Kang J. Association of Sleep Duration with Asthma and Allergic Rhinitis in South Korea: A Nationwide Representative Study. Allergy (2026) 81(4):1306-1309. Epub 20260211. doi: 10.1111/all.70257.
  5. Kim HJ, Yim Y, Nehs CJ, Park J, Kim S, Papadopoulos NG, Kang J, Yon DK. Maternal Opioid Use and Subsequent Risk of Allergic Diseases in Children: Emulation of Target Trials Using the Korean Nationwide Birth Cohort. Allergy (2026) 81(4):1293-1296. Epub 20260122. doi: 10.1111/all.70231.
  6. Kang J, Yim Y, Kang SM, Kang S, Heo YM, Jo H, Lee DG, Kim HJ, Yon DK, Nehs CJ. Subtype-Specific Efficacy of Topical Streptococcus Postbiotic Emollient in Adolescents and Adults with Atopic Dermatitis and Comorbid Allergies: A Post-Hoc Analysis of a Randomized, Double-Blind, Vehicle-Controlled Trial. Allergy, Asthma and Immunology Research (2026) In Press.
  7. Kang J, Son Y, Yim Y, Cho H, Kim J, Lark ARS, Mir FA, Kim HJ, Park J, Lee H, Kim T, Fond G, Boyer L, Rahmati M, Smith L, Yon DK, Nehs CJ. Biomarkers for Alzheimer’s Disease across Diverse Biological Domains: An Umbrella Review and Evidence Map. J Adv Res (2026) 82:917-936. Epub 20250717. doi: 10.1016/j.jare.2025.07.022. PMC13001047
  8. Kang J, Kim HJ, Yim Y, Kim S, Yon DK, Nehs CJ. Genetic Confounding in the Association between Obesity-Related Phenotypes and Neuropsychiatric Disorders. J Affect Disord (2026):121971. Epub 20260515. doi: 10.1016/j.jad.2026.121971.
  9. Kang J, Kim HJ, Yim Y, Kim MS, Park J, Son Y, Fond G, Boyer L, Yon DK, Nehs CJ. Wearable-Derived Rem Sleep as a Modifiable Risk Factor for Cardiovascular Disease: A Multimodal Prediction Model in the All of Us Research Program. Prog Cardiovasc Dis (2026). Epub 20260304. doi: 10.1016/j.pcad.2026.03.002.
  10. Kang J, Kim HJ, Nehs CJ, Yon DK. Step Counts over Time with the Burden of 105 Non-Communicable Diseases in Older Adults from the All of Us Research Program. Arch Gerontol Geriatr (2026) 144:106187. Epub 20260221. doi: 10.1016/j.archger.2026.106187. PMC13014346
  11. Kang J, Kim HJ, Lark ARS, Mir FA, Park J, Son Y, Fond G, Boyer L, Rahmati M, Smith L, Yon DK, Nehs CJ. Association of Everyday Discrimination with Drug Use during the Covid-19 Pandemic in the All of Us Research Program. Psychiatry Investig (2026) 23(1):118-129. Epub 20251226. doi: 10.30773/pi.2025.0234. PMC12835635
  12. Kang J, Kim HJ, Jo Y, Smith KJ, Lark ARS, Mir FA, Park J, Lee H, Kim Y, Rahmati M, Smith L, Rhee SY, Son Y, Yon DK, Nehs CJ. Gestational Diabetes Mellitus and Adverse Maternal and Neonatal Health Outcomes: An Umbrella Review of Meta-Analyses. Obes Rev (2026):e70102. Epub 20260223. doi: 10.1111/obr.70102.
  13. Jang W, Cho H, Kim S, Boyer L, Fond G, Kang J, Nehs CJ, Pizzol D, Lee S, Oh J, Kim HJ, Son Y, Lee H, Yon DK. Global Burden of Anxiety, Depression, and Self-Harm (1990-2021) and the Impact of the Covid-19 Pandemic. J Affect Disord (2026) 392:120201. Epub 20250905. doi: 10.1016/j.jad.2025.120201.
  14. Byun S, Kim K, Jo H, Nehs CJ, Pizzol D, Yon DK, Kang J. Long-Term Trends in Counseling for Stress and Depression among Adults, 2009-2024, Considering the Impact of Covid-19 Pandemic: A Nationwide Representative Study in South Korea. Psychiatry Investig (2026) 23(4):556-575. Epub 20260406. doi: 10.30773/pi.2025.0463. PMC13084277
  15. Son Y, Hong S, Yim Y, Kim S, Lee H, Lee K, Kim HJ, Jo H, Park J, Oh J, Lee S, Lee H, Nehs CJ, Smith L, Yon DK, Kang J. Global Prevalence of Cannabis and Amphetamine/Methamphetamine Use among Adolescents in 47 Countries: A Population-Based Study from Who Database. World J Pediatr (2025) 21(3):291-305. Epub 20250320. doi: 10.1007/s12519-025-00883-w.
  16. Siegmann MJ, Parry S, Lark ARS, Mir FA, Choi J, Carpenter AH, Crowley EA, White CG, Kang J, Purdon PL, Nehs CJ. A Ketogenic Diet Decreases Sevoflurane-Induced Burst Suppression in Rats. Brain Res Bull (2025) 223:111274. Epub 20250224. doi: 10.1016/j.brainresbull.2025.111274. PMC11913213
  17. Mir FA, Lark ARS, Nehs CJ. Unraveling the Interplay between Sleep, Redox Metabolism, and Aging: Implications for Brain Health and Longevity. Front Aging (2025) 6:1605070. Epub 20250521. doi: 10.3389/fragi.2025.1605070. PMC12133771
  18. Mir FA, Jha SK, Nehs CJ. Noradrenergic Dysregulation in the Locus Coeruleus: Implications for Neuropsychiatric Disease Pathophysiology- a Systematic Review. Neurosci Biobehav Rev (2025) 179:106442. Epub 20251028. doi: 10.1016/j.neubiorev.2025.106442.
  19. Li Y, Xu Y, Dong Y, Nehs CJ, Xie Z, Zhang Y. Trifluoroacetic Acid Induced a Cyclophilin D-Dependent Cognitive Impairment in Mice. Aging Dis (2025). Epub 20250226. doi: 10.14336/AD.2024.1430.
  20. Lee H, Kim H, Kim HJ, Son Y, Park J, Kim K, Nehs CJ, Pizzol D, Yon DK, Kang J. Trends in Suicidal Ideation and Sadness among Adolescents by Atopic Dermatitis Status, 2007-2024: A Nationwide Representative Study in South Korea. Int Arch Allergy Immunol (2025):1-26. Epub 20251129. doi: 10.1159/000549860. PMC12779284
  21. Kim TH, Lee K, Hwang J, Lee S, Jo H, Cho H, Lee H, Baek HJ, Kang J, Nehs CJ, Fond G, Boyer L, Chung EK, Yon DK. Adverse Event Reports of Seizure for Insomnia Medication from 1967 to 2023. Sci Rep (2025) 15(1):27308. Epub 20250726. doi: 10.1038/s41598-025-11314-1. PMC12297222
  22. Kim S, Son Y, Oh J, Kim S, Jang W, Lee S, Smith L, Pizzol D, Lee J, Lee H, Nehs CJ, Nehs MA, Jung J, Kang J, Yon DK. Global Burden of Brain and Central Nervous System Cancer in 185 Countries, and Projections up to 2050: A Population-Based Systematic Analysis of Globocan 2022. J Neurooncol (2025) 175(2):673-685. Epub 20250728. doi: 10.1007/s11060-025-05164-0.
  23. Kim S, Lee H, Woo S, Lee H, Park J, Kim T, Fond G, Boyer L, Rahmati M, Smith L, Lopez Sanchez GF, Dragioti E, Nehs CJ, Lee J, Kim HJ, Kang J, Yon DK. Global, Regional, and National Trends in Drug Use Disorder Mortality Rates across 73 Countries from 1990 to 2021, with Projections up to 2040: A Global Time-Series Analysis and Modelling Study. EClinicalMedicine (2025) 79:102985. Epub 20241217. doi: 10.1016/j.eclinm.2024.102985. PMC11720110
  24. Kang J, Park J, Kim HJ, Lee H, Fond G, Boyer L, Rahmati M, Nehs CJ, Smith L, Yon DK. Association of Unmet Healthcare Needs with Depressive Symptoms and Covid-19 Pandemic-Related Factors among Adults, 2009-2022: A Nationwide Study in Korea. J Korean Med Sci (2025) 40(47):e307. Epub 20251208. doi: 10.3346/jkms.2025.40.e307. PMC12685598
  25. Kang J, Lee M, Park M, Lee J, Lee S, Park J, Koyanagi A, Smith L, Nehs CJ, Yon DK, Kim T. Slow Gut Transit Increases the Risk of Alzheimer’s Disease: An Integrated Study of the Bi-National Cohort in South Korea and Japan and Alzheimer’s Disease Model Mice. J Adv Res (2024) 65:283-295. Epub 20231213. doi: 10.1016/j.jare.2023.12.010. PMC11518944
  26. Kang J, Lee H, Yu S, Lee M, Kim HJ, Kwon R, Kim S, Fond G, Boyer L, Rahmati M, Koyanagi A, Smith L, Nehs CJ, Kim MS, Sanchez GFL, Dragioti E, Kim T, Yon DK. Effects and Safety of Transcranial Direct Current Stimulation on Multiple Health Outcomes: An Umbrella Review of Randomized Clinical Trials. Mol Psychiatry (2024) 29(12):3789-3801. Epub 20240530. doi: 10.1038/s41380-024-02624-3.
  27. Kang J, Lee H, Park J, Kim HJ, Kwon R, Kim S, Fond G, Boyer L, Rahmati M, Smith L, Nehs CJ, Son Y, Kim S, Lee H, Lee J, Kim MS, Kim T, Yon DK. Comorbid Physical Health Outcomes in Patients with Bipolar Disorder: An Umbrella Review of Systematic Reviews and Meta-Analyses. Asian J Psychiatr (2024) 99:104138. Epub 20240627. doi: 10.1016/j.ajp.2024.104138.
  28. Choi J, Kang J, Kim T, Nehs CJ. Sleep, Mood Disorders, and the Ketogenic Diet: Potential Therapeutic Targets for Bipolar Disorder and Schizophrenia. Front Psychiatry (2024) 15:1358578. Epub 20240214. doi: 10.3389/fpsyt.2024.1358578. PMC10899493
  29. Cheong C, Park J, Park J, Jo H, Lee K, Lee JH, Kim HJ, Choi Y, Kim H, Nehs CJ, Fond G, Boyer L, Rahmati M, Koyanagi A, Smith L, Lopez Sanchez GF, Dragioti E, Woo S, Lee H, Kang J, Kim T, Yon DK. National Trends in Alcohol Consumption, Smoking, Suicide Attempts, and Covid-19 Pandemic-Related Factors among South Korean Adolescents, 2012-2022. Asian J Psychiatr (2024) 97:104085. Epub 20240518. doi: 10.1016/j.ajp.2024.104085.
  30. Vlasov K, Pei J, Nehs CJ, Guidera JA, Zhang ER, Kenny JD, Houle TT, Brenner GJ, Taylor NE, Solt K. Activation of Gabaergic Neurons in the Rostromedial Tegmental Nucleus and Other Brainstem Regions Promotes Sedation and Facilitates Sevoflurane Anesthesia in Mice. Anesth Analg (2021) 132(4):e50-e55. doi: 10.1213/ANE.0000000000005387. PMC7969415
  31. Moody OA, Zhang ER, Vincent KF, Kato R, Melonakos ED, Nehs CJ, Solt K. The Neural Circuits Underlying General Anesthesia and Sleep. Anesth Analg (2021) 132(5):1254-1264. doi: 10.1213/ANE.0000000000005361. PMC8054915
  32. Melonakos ED, Siegmann MJ, Rey C, O’Brien C, Nikolaeva KK, Solt K, Nehs CJ. Excitation of Putative Glutamatergic Neurons in the Rat Parabrachial Nucleus Region Reduces Delta Power during Dexmedetomidine but Not Ketamine Anesthesia. Anesthesiology (2021) 135(4):633-648. doi: 10.1097/ALN.0000000000003883. PMC8440361
  33. Kato R, Zhang ER, Mallari OG, Moody OA, Vincent KF, Melonakos ED, Siegmann MJ, Nehs CJ, Houle TT, Akeju O, Solt K. D-Amphetamine Rapidly Reverses Dexmedetomidine-Induced Unconsciousness in Rats. Front Pharmacol (2021) 12:668285. Epub 20210518. doi: 10.3389/fphar.2021.668285. PMC8167047
  34. Melonakos ED, Moody OA, Nikolaeva K, Kato R, Nehs CJ, Solt K. Manipulating Neural Circuits in Anesthesia Research. Anesthesiology (2020) 133(1):19-30. doi: 10.1097/ALN.0000000000003279. PMC8351362
  35. Taylor NE, Pei J, Zhang J, Vlasov KY, Davis T, Taylor E, Weng FJ, Van Dort CJ, Solt K, Brown EN. The Role of Glutamatergic and Dopaminergic Neurons in the Periaqueductal Gray/Dorsal Raphe: Separating Analgesia and Anxiety. eNeuro (2019) 6(1). Epub 20190219. doi: 10.1523/ENEURO.0018-18.2019. PMC6498422
  36. Siegmann MJ, Athinarayanan SJ, Hallberg SJ, McKenzie AL, Bhanpuri NH, Campbell WW, McCarter JP, Phinney SD, Volek JS, Van Dort CJ. Improvement in Patient-Reported Sleep in Type 2 Diabetes and Prediabetes Participants Receiving a Continuous Care Intervention with Nutritional Ketosis. Sleep Med (2019) 55:92-99. Epub 20190103. doi: 10.1016/j.sleep.2018.12.014.
  37. Zhang H, Zhao H, Zeng C, Van Dort C, Faingold CL, Taylor NE, Solt K, Feng HJ. Optogenetic Activation of 5-Ht Neurons in the Dorsal Raphe Suppresses Seizure-Induced Respiratory Arrest and Produces Anticonvulsant Effect in the Dba/1 Mouse Sudep Model. Neurobiol Dis (2018) 110:47-58. Epub 20171113. doi: 10.1016/j.nbd.2017.11.003. PMC5748009
  38. Vlasov K, Van Dort CJ, Solt K. Optogenetics and Chemogenetics. Methods Enzymol (2018) 603:181-196. Epub 20180319. doi: 10.1016/bs.mie.2018.01.022. PMC6984397
  39. Van Dort CJ. Locus Coeruleus Neural Fatigue: A Potential Mechanism for Cognitive Impairment during Sleep Deprivation. Sleep (2016) 39(1):11-12. Epub 20160101. doi: 10.5665/sleep.5302. PMC4678350
  40. Taylor NE, Van Dort CJ, Kenny JD, Pei J, Guidera JA, Vlasov KY, Lee JT, Boyden ES, Brown EN, Solt K. Optogenetic Activation of Dopamine Neurons in the Ventral Tegmental Area Induces Reanimation from General Anesthesia. Proc Natl Acad Sci U S A (2016) 113(45):12826-12831. Epub 20161024. doi: 10.1073/pnas.1614340113. PMC5111696
  41. Muindi F, Kenny JD, Taylor NE, Solt K, Wilson MA, Brown EN, Van Dort CJ. Electrical Stimulation of the Parabrachial Nucleus Induces Reanimation from Isoflurane General Anesthesia. Behav Brain Res (2016) 306:20-25. Epub 20160310. doi: 10.1016/j.bbr.2016.03.021.
  42. Kenny JD, Chemali JJ, Cotten JF, Van Dort CJ, Kim SE, Ba D, Taylor NE, Brown EN, Solt K. Physostigmine and Methylphenidate Induce Distinct Arousal States during Isoflurane General Anesthesia in Rats. Anesth Analg (2016) 123(5):1210-1219. doi: 10.1213/ANE.0000000000001234. PMC5026857
  43. Van Dort CJ, Zachs DP, Kenny JD, Zheng S, Goldblum RR, Gelwan NA, Ramos DM, Nolan MA, Wang K, Weng FJ, Lin Y, Wilson MA, Brown EN. Optogenetic Activation of Cholinergic Neurons in the Ppt or Ldt Induces Rem Sleep. Proc Natl Acad Sci U S A (2015) 112(2):584-589. Epub 20141229. doi: 10.1073/pnas.1423136112. PMC4299243
  44. Van Dort CJ, Brown EN. Reply to Grace: Role of Cholinergic Neurons in Rapid Eye Movement (Rem) Sleep Control. Proc Natl Acad Sci U S A (2015) 112(29):E3756. Epub 20150629. doi: 10.1073/pnas.1506854112. PMC4517216
  45. Solt K, Van Dort CJ, Chemali JJ, Taylor NE, Kenny JD, Brown EN. Electrical Stimulation of the Ventral Tegmental Area Induces Reanimation from General Anesthesia. Anesthesiology (2014) 121(2):311-319. doi: 10.1097/ALN.0000000000000117. PMC4112744
  46. Chemali JJ, Van Dort CJ, Brown EN, Solt K. Active Emergence from Propofol General Anesthesia Is Induced by Methylphenidate. Anesthesiology (2012) 116(5):998-1005. doi: 10.1097/ALN.0b013e3182518bfc. PMC3339625
  47. Brown EN, Purdon PL, Van Dort CJ. General Anesthesia and Altered States of Arousal: A Systems Neuroscience Analysis. Annu Rev Neurosci (2011) 34:601-628. doi: 10.1146/annurev-neuro-060909-153200. PMC3390788
  48. Van Dort CJ, Baghdoyan HA, Lydic R. Adenosine a(1) and a(2a) Receptors in Mouse Prefrontal Cortex Modulate Acetylcholine Release and Behavioral Arousal. J Neurosci (2009) 29(3):871-881. doi: 10.1523/JNEUROSCI.4111-08.2009. PMC3430130
  49. Van Dort CJ, Baghdoyan HA, Lydic R. Neurochemical Modulators of Sleep and Anesthetic States. Int Anesthesiol Clin (2008) 46(3):75-104. doi: 10.1097/AIA.0b013e318181a8ca. PMC2745232
  50. Buchwalter A, Van Dort C, Schultz S, Smith R, Le IP, Abbott JL, Oosterhouse E, Johnson AE, Hansen-Smith F, Burnatowska-Hledin M. Expression of Vacm-1/Cul5 Mutant in Endothelial Cells Induces Mapk Phosphorylation and Maspin Degradation and Converts Cells to the Angiogenic Phenotype. Microvasc Res (2008) 75(2):155-168. Epub 20070904. doi: 10.1016/j.mvr.2007.08.004.
  51. Stanley KT, VanDort C, Motyl C, Endres J, Fox DA. Immunocompetent Properties of Human Osteoblasts: Interactions with T Lymphocytes. J Bone Miner Res (2006) 21(1):29-36. Epub 20051010. doi: 10.1359/JBMR.051004.
  52. Burnatowska-Hledin MA, Kossoris JB, Van Dort CJ, Shearer RL, Zhao P, Murrey DA, Abbott JL, Kan CE, Barney CC. T47d Breast Cancer Cell Growth Is Inhibited by Expression of Vacm-1, a Cul-5 Gene. Biochem Biophys Res Commun (2004) 319(3):817-825. doi: 10.1016/j.bbrc.2004.05.057.
  53. Van Dort C, Zhao P, Parmelee K, Capps B, Poel A, Listenberger L, Kossoris J, Wasilevich B, Murrey D, Clare P, Burnatowska-Hledin M. Vacm-1, a Cul-5 Gene, Inhibits Cellular Growth by a Mechanism That Involves Mapk and P53 Signaling Pathways. Am J Physiol Cell Physiol (2003) 285(6):C1386-1396. Epub 20030813. doi: 10.1152/ajpcell.00338.2002.